Jermain Defoe scored five as Tottenham Hotspur FC beat Wigan Athletic FC 9-1 to move into the Premier League's top four, and there were also victories for Stoke City FC and Blackburn Rovers FC.
AC Milan lifted themselves to second in Serie A with an entertaining 4-3 victory over Cagliari Calcio, while AS Roma captain Francesco Totti helped himself to a hat-trick as his team downed AS Bari 3-1.
Real Madrid CF replaced FC Barcelona at the top of the Liga after Gonzalo Higuaín scored the only goal against Real Racing Club Santander before the Spanish champions drew with Athletic Club.
Manchester United FC moved above Arsenal FC into second in the Premier League after beating Everton FC, but Chelsea FC remain clear at the top after a 4-0 rout of Wolverhampton Wanderers FC.
FC Rubin Kazan reclaimed the Russian title after drawing with FC Zenit St. Petersburg on Saturday, with coach Kurban Berdyev saying: "We had to prove our success last year was no accident."
AJ Auxerre made the most of slips from FC Girondins de Bordeaux and Olympique Lyonnais to go top of Ligue 1 on Saturday following a 2-0 win at home to AS Monaco FC, their seventh straight victory.
FC Internazionale Milano added to the pressure on their rivals by beating Bologna FC to stretch their lead at the top of Serie A to eight points. Parma FC went third after beating ACF Fiorentina.
FC Barcelona have fallen victim to the swine flu virus ahead of their UEFA Champions League encounter against FC Internazionale Milano with Rafael Márquez the latest player to present symptoms of the illness.
Werder Bremen joined Bayer 04 Leverkusen at the Bundesliga summit after an emphatic 6-0 win at SC Freiburg and there were also key victories for FC Schalke 04 and TSG 1899 Hoffenheim.
Andorra 1-1 Faroe IslandsAndorra picked up their first Group 1 point in qualifying for the 2011 UEFA European Under-21 Championship against the Faroe Islands.
Olympique de Marseille went fourth in Ligue 1 after beating rivals Paris Saint-Germain FC 1-0, with Gabriel Heinze's lone goal moving OM to within three points of leaders FC Girondins de Bordeaux.